Shenzhen Simeiquan Biotechnology Co., Ltd.

Chemical, Weight Loss, Steroid manufacturer / supplier in China, offering Polypeptide Hormones GLP-1 (7-37) Acetate CAS 106612-94-6, Adrenal Cortical Hormone Test Dexamethasones Phosphate Sodium Injection Anti-Inflammatory, 99%High Purity Muscle Steroids Bodybuilding Primobolan Methenolone Acetate 434-05-9 100mg/Ml and so on.

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Polypeptide Hormones GLP-1 (7-37) Acetate CAS 106612-94-6

FOB Price:US $1 - 5 / Piece
Purchase Qty. (Pieces) FOB Price
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2 US $2 / Piece
3 US $3 / Piece
4 US $4 / Piece
5+ US $5 / Piece
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Min. Order: 1 Piece
Port: Shenzhen, China
Production Capacity: 500kg/Month
Payment Terms: T/T, Western Union, Money Gram

Basic Info.

Model NO.:CAS 106612-94-6
Powder:Yes
Customized:Non-Customized
Certification:GMP, HSE, USP, BP
Suitable for:Elderly, Adult
State:Solid
Purity:>98%
Grade:Pharmaceutical Grade
MOQ:10vials/Kit
Delivery:Safely & Timely, Within 24 Hours After Confirming
Quality:Reliable
Product:GLP-1 (7-37) Acetate / Egrifta / Tesamorelin
Molecular Formula:C151h228n40o47
Molecular Weight:3355.74
Appearance:White Powder
CAS No:106612-94-6
Trademark:Simeiquan
Transport Package:According to Customer′s Needs
Specification:Discreet package
Origin:China
HS Code:3004901000

Product Description


CAS 106612-94-6 GLP-1 (7-37) Acetate For The Treatment of Type 2 Diabetes Mellitus

Quick Details:

GLP-1 (7-37) Acetate
Sequence:His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly
Alias : 7-37-Glucagon-likepeptide I (human);Glucagon-relatedpeptide 1 (Rana catesbeiana),3-L-glutamicacid-10-L-valine-16-glycine-17-L-glutamine-23-L-isoleucine-24-L-alanine-27-L-valine-31-glycine-32-de-L-lysine-
Cas No.: 106612-94-6
Molecular Formula: C151H228N40O47
Molecular Weight: 3355.74
Purity (HPLC): 98.0%
Appearance: White powder
Single Impurity (HPLC): 1.0%
Amino Acid Composition: 10% of theoretical
Peptide Content (N%): 80% (by %N)
Water Content (Karl Fischer): 6.0%
Acetate Content (HPIC): 15.0%
Grade : Pharmaceutical Grade
Storage: Closed, below 2 ~ 8ºC preservation
Usage : GLP-1 can obviously improve the blood glucose in type 2 diabetes animal models or patients through a variety of mechanisms, which promote the regeneration and repair of islet beta cells, increase the number of beta cells is particularly significant role, provides a very good prospect for the treatment of type 2 diabetes mellitus.


Description:

Glucagon like peptide -1 (GLP-1) is a brain gut peptides secretion ileal endocrine cells, at present mainly as a target for type 2 diabetes drug action. Because GLP-1 can reduce the inhibition of gastric emptying, intestinal peristalsis, thus helps to control food intake, weight loss. Prospective placebo in 19 cases of obese patients in control, random, double-blind, crossover trial, GLP-1 subcutaneous injection can increase the patients with postprandial satiety, and make each meal diet weight average reduction of 15%. But because GLP-1 is a polypeptide, cannot be administered orally is a major shortcoming.
GLP-1 consists of proglucagon gene expression in pancreatic alpha cells, the main product, expression of proglucagon gene is glucagon, and in the intestinal mucosa of L cells, prohormone converting enzyme (PC1) the proglucagon peptide sequence in the carboxyl end shear, i.e. GLP-1. GLP-1 has 2 kinds of biological active forms, respectively GLP-1 (7-37) and GLP-1 (7-36) amide, both of which only one amino acid sequences different, cyclic activated about 80% GLP-1 from the GLP-1 (7-36 [1,2]) amide.

Application:

Effect of GLP-1 GLP-1 can protect beta cells can act on the pancreatic beta cells, promote the synthesis of insulin, insulin gene transcription and secretion and can stimulate the proliferation and differentiation of islet beta cells, inhibit the apoptosis of pancreatic beta cells, increase the number of beta cell of islet [2-5]. In addition, GLP-1 also can be applied to the pancreatic alpha cells, strongly inhibit the release of glucagon, and act on the islet delta cells, promote the secretion of somatostatin, somatostatin cells and can be used as a paracrine hormone involved in the inhibition of glucagon.
GLP-1 with glucose concentration dependent hypoglycemic effect, i.e. only rise in glucose levels under the condition of GLP-1, only play a hypoglycemic effect, but in normal blood sugar levels, caused no further decrease. The glucose concentration dependence of the GLP-1 is its hypoglycemic properties of clinical application safety of foundation and security, thereby avoiding people may cause severe hypoglycemia in patients with existing drug treatment for diabetes and scheme of worry.
In addition, GLP-1 also has many other biological characteristics and functions, for example, GLP-1 might play a lipid-lowering, antihypertensive effect, so as to have a protective effect on the cardiovascular system; it can also by acting on central reinforcement learning and memory function, protect the nerve.

Competitive Advantage:

1. Rich experience.
Our company is a professional steroid supplier in China over 15 years.Our products have been exported to Germany, Spain, UK, USA, Canada,Brazil,Australia, Middle East, and others.We got very good feedback from our customers, due to the quality of our steroid and professional experience in operating the business.

2. Great quality, purity and favourable.
Good quality is one of our secret of success,both raw powder and liquid steroids.

3. Safe and fast delivery.
There is also steroids at stock, so we can deliver them very quickly as soon as we got the payment,normally within 24 hours.

We have special way that could ship 0.01kg to 3.5kg products at one time. We also offer melting powder into liquid service.And can ship the liquid in special bottles.

4. Good after-sales service.
Tracking the package and updating it every day.Quick response and good communications,online 24 hours.

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Shenzhen Simeiquan Biotechnology Co., Ltd.

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