Shenzhen Simeiquan Biotechnology Co., Ltd.

Doxorubicin HCl, Benzocaine, Lidocaine manufacturer / supplier in China, offering 1g/Foil Antineoplastic Powder Doxorubicin HCl with Competitve Price, Adrenal Cortical Hormone Test Dexamethasones Phosphate Sodium Injection Anti-Inflammatory, 99%High Purity Muscle Steroids Bodybuilding Primobolan Methenolone Acetate 434-05-9 100mg/Ml and so on.

Supplier Homepage Product List Pharmaceutical intermediates 1g/Foil Antineoplastic Powder Doxorubicin HCl with Competitve Price

1g/Foil Antineoplastic Powder Doxorubicin HCl with Competitve Price

FOB Price:US $1 - 1 / /
Purchase Qty. (g) FOB Price
1-9 US $1 / /
10+ US $1 / /
Get Latest Price
Min. Order: 1 g
Production Capacity: 5kg/Month
Transport Package: 0.001kg/Foil or as Require
Payment Terms: T/T, Money Gram, Western Union, Bank transfer

Basic Info.

Model NO.:25316-40-9
Powder:Yes
Customized:Non-Customized
Certification:BP
Suitable for:Adult
State:Solid
Purity:>99%
Product Name:Doxorubicin HCl
CAS:25316-40-9
Appearance:Orange-Red or Red Crystalline Powder
Mf:C27h30clno11
MW:579.98
Einecs:246-818-3
Trademark:Simeiquan
Specification:ISO9001
Origin:China
HS Code:3001200020

Product Description

Doxorubicin hydrochloride
CAS: 25316-40-9
MF: C27H30ClNO11
MW: 579.98
EINECS: 246-818-3
Synonyms: ADRIACIN;ADRIBLASTINA;ADRIBLASTINA HYDROCHLORIDE;ADRIAMYCIN HCL;ADRIAMYCIN HYDROCHLORIDE;(8s-cis)-10-[(3-amino-2,3,6-trideoxy-alpha-l-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxynaphthacene-5,12-dione hydrochloride;14-HYDROXYDAUNOMYCIN HCL;14-HYDROXYDAUNOMYCIN HYDROCHLORIDE
Appearance:Orange-red or red crystalline powder
Chemical Properties Orange-Red Crystalline Solid
Usage Used as an antineoplastic
Usage Strong fluorescent dye intercalating into DNA. Antitumour antibiotic. Effect of adriamycin on heart mitochondrial DNA. Inhibitor of reverse transcriptase and RNA polymerase; immunosuppressive agent.
Usage Antibacterial;DNA intercalant

Usage Doxorubicin hydrochloride (adriamycin hydrochloride) is an antitumour agent that has been formulated as a salt to achieve higher water solubility. While the salt shares the same pharmacological properties as doxorubicin free base, its greater water solubility may offer advantages in some in vitro applications. Physicochemical properties and chromatographic behaviour will depend on whether the pH is buffered. In non-pH controlled systems the free base and salt may behave differently.
General Description Orange-red thin needles. Aqueous solutions yellow-orange at acid pHs, orange-red at neutral pHs, and violet blue over pH 9.

Air & Water Reactions Water soluble.
Reactivity Profile Amines, like Doxorubicin hydrochloride, are weak chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Fire Hazard Doxorubicin hydrochloride is probably combustible.
Biological Activity Antitumor antibiotic agent that inhibits DNA topoisomerase II. DNA intercalator that inhibits nucleic acid synthesis and induces apoptosis.
Items TestedSpecificationResult
Purity98.0~102.0%99.02%
Description
Orange-red or red crystalline powder; No visible
evidence of contamination by foreign matter.

Confirm
Identification AIR spectrum corresponds to the IR spectrum of the reference standardConfirm
Identification B
The retention time of the doxorubicin peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.

Confirm
SolubilitySoluble in water and methanol; slightly soluble in ethanol; practically insoluble in acetone.Conforms
Residual Solvents
 

 
Acetone≤ 0.5%0.31%
Acetone +Ethanol≤ 2.5%0.60%
methanol≤ 0.3%Not detected
Dichloromethane≤ 0.06%Not detected
pH4.0 to 5.55.1
Water Content≤ 4.0%0.8%
Related Substances
 

 
Impurity A (Doxorubicinone)≤ 0.5%0.1%
Any Other unknown Impurity≤ 0.1%0.07%
Total unknown Impurities≤ 0.3%0.2%
Total Impurities≤ 1.0%0.9%
ConclusionIt complies to reference standard

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Competitive Advantages:
1. Professional raw powder factory in China, all powders are factory directly supplying. Have over 10 years' honour.
2. We exported to all over the world such as Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Australia, Japan, Korea and so on, over 100kgs each month.
3. Most of powders are in stock, Chargeable samples are available, Could be shipped out within 24hours.
4. Our products and services will focus on the largest customer demand. We hold the greatest enthusiasm and sincere cooperation with each customer.
5. A discount would be given when you make a large order.

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Shenzhen Simeiquan Biotechnology Co., Ltd.

- Guangdong, China
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