Naphazoline HCl Anti Inflammatory Analgesic Powder CAS: 550-99-2
Product Name: Naphazoline hydrochloride
Synonyms: 2-(1-Naphthylmethyl)-2-imidazoline hydrochloride; Naphazoline HCl; Naphthasoliumchloride; Privinehydrochloride;
CAS No.: 550-99-2
EINECS No.: 208-989-2
Molecular Formula: C14H15ClN2
Molecular Weight: 246.74
Melting point: 254-260 ° C
Boiling point: 440.5° C at 760 mmHg
Flashing point: 220.2° C
Solubillity in water: 170 g/L (20º C)
Appearance: White to off-white crystaline powder
Packing: 1kg/foil bag
Application: Sympathomimetic agent, vasoconstrictor
Naphazoline hydrochloride is the common name for 2-(1-naphthylmethyl)-2-imidazoline hydrochloride. It is a sympathomimetic agent with marked alpha adrenergic activity. It is a vasoconstrictor with a rapid action in reducing swelling when applied to mucous membrane. It acts on alpha-receptors in the arterioles of the conjunctiva to produce constriction, resulting in decreased congestion. It is an active ingredient in several over-the-counter formulations including Clear Eyes and Naphcon eye drops.
Naphazoline is a decongestant used to relieve redness, puffiness, and itchy/watering eyes due to colds, allergies, or eye irritations (smog, swimming, or wearing contact lenses). It is known as a sympathomimetic (alpha receptor agonist) that works in the eye to decrease congestion.
Some brands of naphazoline eye drops also contain other ingredients. Lubricants (such as glycerin, hypromellose, or polyethylene glycol 300) help protect the eyes from more irritation. Zinc sulfate, an astringent, helps reduce redness and irritation.
|Appearance||White crystalline powder||Pass|
|Loss on drying||0.50% Max||0.10%|
|Residue on ignition||0.20% max||0.08%|
|Total impurities||not more than 2.0%||Pass|
|Alcohol||Not more than 300 ppm||Pass|