Shenzhen Simeiquan Biotechnology Co., Ltd.

Melanotan 2, Melanotan, Mt2 manufacturer / supplier in China, offering Melanotan 2 (10mg) Melanotan II /Mt-2 UK Buy Tans Igf-1lr3 Gym, Anti-Estrogenic Muscle Growth Burning Fat Steriod Drostanolone Propionate Masteron P, Factory Supply Polypeptide Hormones Enfuvirtide Acetate (T-20) for HIV/Aids and so on.

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Melanotan 2 (10mg) Melanotan II /Mt-2 UK Buy Tans Igf-1lr3 Gym

FOB Price:US $5.2 / vials
Min. Order (vials) FOB Price
10+ US $5.2 / vials
Get Latest Price
Min. Order: 10 vials
Port: Hong Kong, Hong Kong
Production Capacity: 50000vials/Month
Payment Terms: T/T, Western Union, Money Gram, Bit Coin

Basic Info.

Model NO.:121062-08-6
Powder:Yes
Customized:Non-Customized
Certification:ISO 9001
Suitable for:Adult
State:Solid
Purity:>98%
Product Name:Melanotan II
CAS:121062-08-6
Appearance:White Crystalline Powder
Purity (HPLC):99.3%
Unit Size:10mg/Vial
Usage:Muscle Building and Skin Tanning
Trademark:Simeiquan
Transport Package:10vials/Kit or as Require
Specification:ISO9001
Origin:China
HS Code:3001200020

Product Description

Melanotan II

Melanotan 2 (10mg) Melanotan II /Mt-2 UK Buy Tans Igf-1lr3 Gym

Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2 
Molecular formula: C50H69N15O9 
Molar Mass: 1024.180 
CAS number: 121062-08-6 
PubChem: 92432 
MeSH: melanotan-II 
Melanotan 2 Structural Name: Ac-cyclo[Nle4, Asp5, D-Phe7, Lys10]α-MSH4-10-NH2


 

Melanotan 2 Studies and Further Information

Melanotan and Melanotan 2 are both analogs of the peptide hormone alpha-melanocyte stimulating hormone (α-MSH) that tend to induce skin tanning. Unlike Melanotan 1, Melanotan 2 has been shown to have aphrodisiac properties, the additional effect of increasing libido. Melanotan 2 is a cyclic heptapeptide analog of the alpha-melanocyte stimulating hormone (a-MSH).

The effects of Melanotan 2 on the diet and food intake of the laboratory mice have also been investigated. It has been demonstrated that the central melanocortin (MC) has been activated by melanotan 2 when fed and induced in the mice. The six-day treatment of Melanotan 2 has shown that the peptide actually reduced the body weight and the adipose tissue in the viscera of the mice and suppressed the caloric intake of the organism. This has implications in clinical applications of the possible treatment to reduce carbohydrate or calorie intake especially for the overweight and the obese. Furthermore, the same study has also demonstrated that there was a sustained increase in the available oxygen consumption in obese animals. Melanotan 2 also helped reduced the level of serum insulin and the cholesterol levels when compared with the control treatments. Furthermore, it has been suggested that melanotan 2 actually lowers the level of acetylcholine A caboxylase expression and even prevented the reduction of carnitine and palmitoltransferase I mRNA in muscle-type tissues by pair-feeding in the muscles of the obese rats. Moreover, the Melanotan 2 peptide actually increased the fat catabolism in the muscles and even improved the cholesterol metabolism (Li et al. 2004).

 

Melanotan 2 (also referred to as Melanotan II) is a synthetically produced variant of a peptide hormone naturally produced in the body that stimulates melanogenesis, a process responsible for pigmentation of the skin. This peptide hormone, called alpha-Melanocyte stimulating hormone or MSH, activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan 2 has been shown in studies to exhibit appetite suppressant, lipolytic, and libido-enhancing effects in addition to promoting skin tanning. Melanotan 2 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties. 

Additionally, Melanotan 2 and a similar synthetically produced variant, known as PT-141, have been studied at length as a potential remedy for the treatment of sexual dysfunction; specifically, male erectile dysfunction

 

The Development of Melanotan 2

The initial creation of the synthetic Melanotan 2 peptide can be credited to the University of Arizona. During the course of research aimed at developing a defense against skin cancer, focus was placed on developing a method of stimulating natural melanogenesis, or the natural production of melanin in the skin, without direct exposure to the potentially harmful ultraviolet radiation in sunlight. Initially, University of Arizona researchers attempted to directly administer the naturally occurring hormone alpha-MSH in order to elicit this desired result. Although this strategy exhibited promising results, it was determined that the naturally occurring MSH had a prohibitively short half-life to be of realistic use as a therapeutic remedy. However, the positive results gleaned from MSH administration encouraged further research into the development of Melanotan 1 and Melanotan 2, which exhibit similar effects whilst possessing an extended half-life for functional therapeutic utilization.

 

Melanotan 2 Studies and Further Information

Melanotan and Melanotan 2 are both analogs of the peptide hormone alpha-melanocyte stimulating hormone (α-MSH) that tend to induce skin tanning. Unlike Melanotan 1, Melanotan 2 has been shown to have aphrodisiac properties, the additional effect of increasing libido. Melanotan 2 is a cyclic heptapeptide analog of the alpha-melanocyte stimulating hormone (a-MSH).

The effects of Melanotan 2 on the diet and food intake of the laboratory mice have also been investigated. It has been demonstrated that the central melanocortin (MC) has been activated by melanotan 2 when fed and induced in the mice. The six-day treatment of Melanotan 2 has shown that the peptide actually reduced the body weight and the adipose tissue in the viscera of the mice and suppressed the caloric intake of the organism. This has implications in clinical applications of the possible treatment to reduce carbohydrate or calorie intake especially for the overweight and the obese. Furthermore, the same study has also demonstrated that there was a sustained increase in the available oxygen consumption in obese animals. Melanotan 2 also helped reduced the level of serum insulin and the cholesterol levels when compared with the control treatments. Furthermore, it has been suggested that melanotan 2 actually lowers the level of acetylcholine A caboxylase expression and even prevented the reduction of carnitine and palmitoltransferase I mRNA in muscle-type tissues by pair-feeding in the muscles of the obese rats. Moreover, the Melanotan 2 peptide actually increased the fat catabolism in the muscles and even improved the cholesterol metabolism (Li et al. 2004).

 

α-Melanocyte-Stimulating Hormone Analogues (Melanotan Peptides)

α-Melanocyte-stimulating hormone (α-MSH) is a naturally occurring endogenous melanotan peptide hormone of the melanocortin family, which is considered to be the most important of the melanocyte-stimulating hormones when it comes to stimulating melanogenesis, a process which in mammals is responsible for hair and skin pigmentation. α-MSH also plays a role in feeding behavior, energy homeostasis, and sexual activity (Bremelanotide and Melanotan 2). α-MSH is a nonselective agonist of melanocortin receptors MC1, MC3, MC4 and MC5. Melanotan 1 and Melanotan 2 activate the MC1 receptor, which is responsible for effects on skin pigmentation. Melanotan 2 and PT-141 both stimulate the MC3 and MC4 receptors which are responsible for the regulation of appetite, metabolism, and sexual behavior. However, PT-141 Bremelanotide does not stimulate the MC1 receptor.

A few synthetic analogues of α-MSH have been investigated for their apparent photoprotective effects against ultraviolet (UV) radiation from the sun, namely Melanotan (afamelanotide) and Melanotan II, referred to as Melanotan 2. Bremelanotide, another analogue of α-MSH similar to Melanotan 2, is currently under development for the treatment of sexual dysfunction. All of these melanotan peptides have significantly greater potencies than α-MSH, but with distinctive selectivity peptide profiles.

Buy Melanotan, Melanotan 2 and PT-141 Supplier

PeptideSciences™, the leading Melanotan 2 supplier, proudly offers a large selection of premium quality α-MSH analogues that are assayed at a minimum purity of 99%. We understand the great importance of purchasing only the highest quality melanotan peptides online to ensure maximum potency (stability) and purity of your Melanotan 1, Melanotan 2 and PT-141 when you shop online.

 
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Melanotan 2 (10mg) Melanotan II /Mt-2 UK Buy Tans Igf-1lr3 Gym
 
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